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Asian Journal of Research in Chemistry
Year : 2017, Volume : 10, Issue : 2
First page : ( 106) Last page : ( 11)
Print ISSN : 0974-4169. Online ISSN : 0974-4150.
Article DOI : 10.5958/0974-4150.2017.00016.5

Synthesis and Character cterization of Schiff Base CoII, NiII and CuII Complexes derived from 2-Hydroxy-1-naphthaldehyde and Ethyle enediamine

 Kadhiravansivasamy*, Sivajiganesan S., Periyathambi T., Nandhakumar V., Pugazhenthi M.

Department of Chemistry, A.V.V.M Sri Pushpam College Poondi, Thanjavur, Tamilnadu, India

*Correspondining Author E-mail: kadhiravansivasamy@gmail.com

Online published on 17 July, 2017.

Abstract

New CoII, NiII and CuII complex ha as been synthesized and characterized by elemental annalysis, UV-Vis, FT-IR and thermal analysis Binding of this is CoII, NiII and CuII complex with calf thymus DNA w was investigated by UV-Visible absorption, fluorescence sp pectroscopy techniques. The intrinsic binding constan nts Kb of complex with CT-DNA obtained from UV-Vis a absorption studies. Further, the in vitro cytotoxic e effect of the complexes examined on cancerous cell line, succh as human breast cancer cells (MCF-7).

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Keywords

CoII, NiII and C CuII complex, DNA interaction, Electrochemical st tudies and cytotoxicity activity.

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