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Asian Journal of Pharmacy and Technology
Year : 2018, Volume : 8, Issue : 2
First page : ( 88) Last page : ( 91)
Print ISSN : 2231-5705. Online ISSN : 2231-5713.
Article DOI : 10.5958/2231-5713.2018.00014.4

Evaluation Ixora coccinea Formulation for antibacterial and antioxidant activity.

Prof. Patil Sushil D.*, Chande Bhavini D., Budukhale Kirti M., Damare Radhika V., Kale Nilam, Pathak Shivangi S.

Department of Pharmaceutical Chemistry, MET's Institute of Pharmacy, Bhujbal Knowledge City, Adgaon Nashik, Maharashtra, India

*Corresponding Author E-mail: sushilpharma@rediffmail.com

Online published on 21 July, 2018.

Abstract

Present investigation was to develop novel formulation methanolic extract of Ixora coccinea leaves (ICF-ME), which is reported to possess Anti-oxidant activityanti-bacterial activitiesandantimicrobial activity. Ixora coccinea formulation showed significant activities antibacterial and antioxidant assays compared to the standard antioxidant in a dose dependent manner and remarkable activities to scavenge reactive oxygen species (ROS). Staphylococcus aureus and E. coli was evaluated by the standard cup plate method and the inhibition zone diameters were measured for antibacterial activity. It is evident that formulation F-4 containing both clove oil (0.7%) and Ixora coccinea (7%) showed larger zone of inhibition in comparison to other formulations. So antibacterial and antioxidant activity of formulation F-4 found to be superior to other formulations. Results of all other evaluation parameters of F-4 were also satisfactory among all the formulations.

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Keywords

Formulation, antioxidantactivity, Ixora coccinea, antibacterial.

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