(3.237.71.23)
Users online: 2997    [ij] [ij] [ij] 
Email id
 

Asian Journal of Pharmacy and Technology
Year : 2016, Volume : 6, Issue : 3
First page : ( 141) Last page : ( 147)
Print ISSN : 2231-5705. Online ISSN : 2231-5713.
Article DOI : 10.5958/2231-5713.2016.00020.9

Recent Approaches in Floating Drug Delivery System

Shinkar Dattatraya M.1,*, Suryawanshi Amol P.1, Saudagar Ravindra B.2

1Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik

2Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik

*Corresponding Author E-mail: amol2304@gmail.com

Online published on 18 October, 2016.

Abstract

The oral drug delivery systems exhibit variable and short gastric emptying time, which result in incomplete drug release from the delivery system. This leads to diminished efficacy of administered dose. Floating drug delivery system (FDDS) can retain the dosage form in the gastric region for several hrs. Designing the Floating drug delivery system for prolong gastric retention helps in improving bioavailability and improve solubilityof the drug that are less soluble in a high pH environment. FDDS applicable for drugs having poor bioavailability because of narrow absorption window in the GIT. FDDS increase the bioavailability of drug by retains the dosage form at the site of absorption. This review mainly focus on information on the basis o their design, classification, advantages, evaluation and future scope of FDDS.

Top

Keywords

Floating drug delivery system, gastric residence time, swelling index, buoyancy.

Top

  
║ Site map ║ Privacy Policy ║ Copyright ║ Terms & Conditions ║ Page Rank Tool
446,113,670 visitor(s) since 30th May, 2005.
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.