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Asian Journal of Pharmacy and Technology
Year : 2015, Volume : 5, Issue : 3
First page : ( 153) Last page : ( 157)
Print ISSN : 2231-5705. Online ISSN : 2231-5713.
Article DOI : 10.5958/2231-5713.2015.00022.7

An Overview about Medicinal Chemistry and Pharmaceutical Applications of 2, 4-Imidazolidinone and its Derivatives

Sudani Bhadreshkumar R.1,*, Desai Vikas A.2

1Government Engineering College, Valsad, Near Sanskar Kendra, Tithal Road, Valsad-396001

2B.K.M. Science College, Near Sanskar Kendra, Tithal Road, Valsad-396001

*Corresponding Author E-mail: brsudani@yahoo.com

Online published on 29 January, 2016.

Abstract

2,4-imidazolidinedione is a heterocyclic compound commonly well known as Hydantoin. Starting from its first synthesis it is found interesting among the medicinal and pharmaceutical chemists. In this review article we have briefly described different methods of synthesis with the help of some name reactions like Buchere-Bergs reaction and Diels-Alder reaction. It is found that this molecule is synthesized with three substitutions where different organic reactive groups imports different pharmacological properties in the molecules of hydantoin derivatives. The broad pharmacological activities of 2,4-imidazolidinedione is also discussed in this work for more than 16 dieses. This review article will be very good useful for scholars and scientists to explore more possibilities with other derivatives using the methods given in this review paper.

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Keywords

Hydantoin, Allantoin, Imidazolidinedione, Heterocyclic, phenyl urea.

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