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Asian Journal of Pharmacy and Technology
Year : 2015, Volume : 5, Issue : 3
First page : ( 129) Last page : ( 137)
Print ISSN : 2231-5705. Online ISSN : 2231-5713.
Article DOI : 10.5958/2231-5713.2015.00020.3

An Overview on Fast Dissolving Oral Films

Chonkar Ankita D.1, Bhagawati S. T.2, Udupa N.1,*

1Manipal College of Pharmaceutical Sciences, Manipal University, Manipal

2Sree Siddaganga College of Pharmacy, Thumkur

*Corresponding Author E-mail: n.udupa@manipal.edu

Online published on 29 January, 2016.

Abstract

Research and developments in oral drug delivery has evolved to changeover of solid dosage forms from conventional solid tablets/capsules to mouth dissolving drug delivery system (MDDS). Intension behind the development of MDDS was to provide the patients with more conventional means of taking their medication. But in MDDS, dissolution of drug in saliva offers the oral transmucosal absorption of the drug to reach to the systemic circulation. Concept of orotransmucosal drug delivery results into various dosage forms which allows orotransmucosal absorption of the drug. Oral strip is the thin film fabricated using hydrophilic polymers that rapidly dissolves beneath the tongue or in buccal cavity and dissolved drug gets absorbed through the oral mucosal surface to reach to the systemic circulation. Here in this review, formulation consideration, manufacturing, physical evaluation of oral films have been discussed.

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Keywords

Oral Films, Transmucosal, MDDS, Hydrophilic polymers, orotransmucosal.

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