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Asian Journal of Pharmacy and Technology
Year : 2020, Volume : 10, Issue : 3
First page : ( 143) Last page : ( 148)
Print ISSN : 2231-5705. Online ISSN : 2231-5713.
Article DOI : 10.5958/2231-5713.2020.00025.2

Evaluation of phytochemical and In vitro anti-inflammatory activity of leaf and fruit extracts of Casuarina equisetifolia

Mamillapalli Vani1,*, Chapala Ratna Harika1, Sareddu Tejaswi Komal Sai1, Kondaveeti Latha Sri1, Pattipati Santhi1, Khantamneni Padmalatha2

1Department of Pharmacognosy and Phytochemistry, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu-521108, Vijayawada, Krishna (Dt.), Andhra Pradesh, India

2Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu-521108, Vijayawada, Krishna (Dt.), Andhra Pradesh, India

*Corresponding Author E-mail: vanimamillapalli@yahoo.co.in

Online published on 16 September, 2020.

Abstract

The plant Casuarina equisetifolia, commonly called as horse tail belonging to family Casuarinaceae is used traditionally for the treatment of infections, ulcers, cough, diarrhea etc. The plant is a rich source of tannins and flavonoids. In the current study the plant leaf, fruit aqueous and ethanolic extracts were determined for total flavonoid content followed by in vitro anti-inflammatory activity study by HRBC membrane stabilization and protein denaturation assays. The results indicate that highest amount of rutin equivalent flavonoids were present in ethanolic extract of leaf, aqueous and ethanolic extracts of fruit. Fruit extracts exhibited highest % inhibition of lysis of HRBC. Aqueous leaf and fruit extracts exhibited highest inhibition of protein denaturation, The results indicate that further in vivo studies, phytochemical isolation, characterization studies could be conducted for plant extracts

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Keywords

Casuarina equisetifolia, Total flavonoid, Anti-inflammatory, HRBC lysis, Protein denaturation.

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