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Asian Journal of Pharmaceutical Research
Year : 2018, Volume : 8, Issue : 3
First page : ( 145) Last page : ( 147)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.5958/2231-5691.2018.00025.4

Evaluation of In Vitro Anti Inflammatory activity of Kusta Gaja Kesari-A Siddha Herbo Mineral Formulation against Albumin Protein Denaturation

Sureka A.1,*, Sharmila C. Mary2, Devi R. Chithra3, Kumar N. J. Muthu4, Banumathi V.5

1Emergency Medical Officer, National Institute of Siddha, Tambaram Sanatorium

2Resident Medical Officer, National Institute of Siddha, Tambaram Sanatorium

3House Officer, National Institute of Siddha, Tambaram Sanatorium

4Associate Professor, Hospital Superintendent, National Institute of Siddha, Tambaram Sanatorium

5Director, National Institute of Siddha, Tambaram Sanatorium

*Corresponding Author E-mail: eva.sureka@gmail.com

Online published on 24 October, 2018.

Abstract

Aim: The present study is conducted to evaluate the In Vitro Anti Inflammatory activity of Kusta Gaja Kesari (KGK) against Protein (Albumin) Denaturation. Methods: The test drug (KGK) at varying concentration ranges from 100 to 500 μg/ml is incubated and heated with Egg albumin in controlled experimental conditions. The percentage inhibition of the protein denaturation is calculated. Diclofenac sodium is used as reference standard drug. Result: The results from the present study clearly indicates that the test drug KGK is effective in inhibiting heat induced protein denaturation. A maximum percentage of inhibition of 51.21% was observed at 500 μg/ml when compared with the standard.

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Keywords

Anti inflammatory activity, Kusta Gaja kesari, Protein Denaturation Assay, Siddha, Skin diseases.

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