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Asian Journal of Pharmaceutical Research
Year : 2018, Volume : 8, Issue : 2
First page : ( 71) Last page : ( 77)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.5958/2231-5691.2018.00012.6

Development and Characterization of Orange Peel Extract Based Nanoparticles

Vinay C H1,*, Goudanavar Prakash1, Acharya Ankit1, Ahmed Mohammed Gulzar2, Kumar Prem S3

1Research Scholar, Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, B. G. Nagara, Karnataka-571 448

2Professor and Principal, Yenepoya College and Research centre, Yenepoya University, Mangalore-575 018

3JRF, Novel Drug Design and Discovery Laboratory Department of Pharmaceutical Chemistry, SETs College of Pharmacy, S R Nagara, Dharwad, Karnataka-580002

*Corresponding Author E-mail: vinaykalyani9743@gmail.com

Online published on 7 July, 2018.

Abstract

The main objective of the present work was to prepare orange peel extract based nano particles by chemical complexation method. Ethanolic extracts of orange peel were prepared by using Soxhlet apparatus and evaluated for phyto-chemical constituents. Qualitative analysis showed that orange peel extract showed positive results for alkaloids, tannin and saponins. The percentage moisture content and pH of the extract was found to be 96.1% and 3.8 respectively. A zeta potential and particle size of prepared nanoparticles was found in the range of-32.0 mV to-21.4 mV and 178.8 nm to 191.6 nm, respectively. These range confirms that obtained particles were in nano range, i.e. <500 nm size. SEM results indicated the formation of nanoparticles and were relatively spherical in shape. Energy dispersive spectrometry (EDS) analysis confirms the presence of AgNPs. Further the study will be extended for anti-microbial and wound healing activities.

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Keywords

Pomegranate peel extract, Qualitative analysis, Nano particles.

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