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Asian Journal of Pharmaceutical Research
Year : 2017, Volume : 7, Issue : 1
First page : ( 30) Last page : ( 34)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.5958/2231-5691.2017.00006.5

Pharmaceutical Importance and Significance of Limit Tests

Ahmed Habeeb1,*, Ehtesham Mohammed1, Rasheed Nuha2, Mohammad Abdul Saleem3,*

1Department of Pharma. D, Nizam Institute of Pharmacy, Deshmukhi (V), Pochampally (M), Behind Mount Opera, Yadadri (Dist)-508284, Telangana, India

2Department of Pharmaceutics, Nizam Institute of Pharmacy, Deshmukhi (V), Pochampally (M), Behind Mount Opera, Yadadri (Dist)-508284, Telangana, India

3Department of Pharmaceutical Analysis and Quality Assurance, Nizam Institute of Pharmacy, Deshmukhi (V), Pochampally (M), Behind Mount Opera, Yadadri (Dist)-508284, Telangana, India

*Corresponding Author E-mail: mohdsaleempharma@gmail.com

Online published on 18 September, 2017.

Abstract

The present subject is on the review of various limit test and titrations which are commonly conducted in the Chemistry lab. Limit tests are a category of impurity tests in which a solution of an unknown sample is compared to a standard that contains the impurity at the product limit. Generally this definition applies to limit tests that are in widespread use in various pharmacopoeial compendia, such as United States Pharmacopoeia (USP), European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP) and Food Chemicals Codex (FCC). These tests are used to make a simple pass/fail evaluation of the sample. Typically this category of test relies on the comparison of an unknown sample to a standard solution. Often these tests rely on a visual evaluation by the technician, though some may rely on instrumental analysis of the sample.

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Keywords

Limit tests, Arsenic, end point, titration, equivalent point, and indicator.

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