(18.207.102.38)
Users online: 2131    [ij] [ij] [ij] 
Email id
 

Asian Journal of Pharmaceutical Research
Year : 2016, Volume : 6, Issue : 3
First page : ( 123) Last page : ( 130)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.5958/2231-5691.2016.00019.8

Docking of Hematoporphyrin on Various Anticancer Drugs Targeting Enzymes

Nandhini S1,*, Radha R2,**, Vadivu R3

1PG Scholar, Department of Pharmacognosy, College of Pharmacy, Madras Medical College, Chennai, India

2Professor & Head of the Department, Department of Pharmacognosy, College of Pharmacy, Madras Medical College, Chennai, India

3Assiatant Professor, Department of Pharmacognosy, College of Pharmacy, Madras Medical College, Chennai, India

*Corresponding Author E-mail: nandypharma1787@gmail.com

** rradha1970@gmail.com

Online published on 18 October, 2016.

Abstract

The present study deals with docking of Hematoporphrin with various anticancer drugs targeting enzymes. The targets used were PDB-ID 2Y3I, PDB-ID 3OZZ, PDB-ID 3UEN and PDB-ID 4O33. Hematoporphyrin docked with these enzymes and interactions between the enzyme and compound were measured and compared with standard Paclitaxel. The study concluded that, the compound (Hematoporphyrin) isolated from plant were high interactions with PDB-ID 4O33 when compared to standard.

Top

Keywords

Docking, Hematoporphyrin, Paclitaxel, Protein Data Bank, interactions.

Top

  
║ Site map ║ Privacy Policy ║ Copyright ║ Terms & Conditions ║ Page Rank Tool
451,663,181 visitor(s) since 30th May, 2005.
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.