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Asian Journal of Pharmaceutical Research
Year : 2016, Volume : 6, Issue : 1
First page : ( 31) Last page : ( 34)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.5958/2231-5713.2016.00005.2

Need and Application of Analytical Method Development on New Fixed Dose Combination of Irbesartan and Atorvastatin in Pharmaceutical Industry

Paras Virani1,2,*, Kinjal Virani

1Research Scholar 2014, Gujarat Technological University, Gujarat

2Quality assurance department, Shree Dhanvantary Pharmacy College, Kim, Surat

*Corresponding Author E-mail: parasvirani@gmail.com

Online published on 2 April, 2016.

Abstract

Analytical method is primary requirement of the pharmaceutical industry. In pharmaceutical industry various analytical methods is used like chromatography, spectroscopy method, electrochemical method, ion incorporating method, etc. Irbesartan is Irbesartan is classified as an angiotensin II receptor type 1 antagonist. Angiotensin II receptor type 1 antagonists are widely used in treatment of diseases like hypertension, heart failure, myocardial infarction and diabetic nephropathy. Atorvastatin is the most efficacious of the currently available HMG-CoA Reductase inhibitors used in anti lipidemic and also used in atherosclerosis, stroke and cardiac risk. In recently approved new fixed dose combination of Irbesartan and atorvastatin in market of Korea so it require analytical method development which help in industry for new drug delivery system development. This review highlights the role, need and application of various analytical techniques for Irbesartan and atorvastatin combination and their corresponding analytical methods in the pharmaceutical industry.

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Keywords

Analytical method, irbesartan, atorvastatin, pharmaceutical industry, fixed dose combination.

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