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Asian Journal of Pharmaceutical Research
Year : 2015, Volume : 5, Issue : 2
First page : ( 83) Last page : ( 89)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.5958/2231-5691.2015.00012.X

Evaluation of In Vitro Anti-Inflammatory Activity of Tephrosia purpurea (Seed)

Anbarasi A., Vidhya R.*

Department of Biochemistry, Dharmapuram Ganambigai Govt. Arts College (W), Mayiladuthurai-609001, Tamilnadu, India

*Corresponding Author E-mail: flowervidu@gmail.com

Online published on 29 October, 2015.

Abstract

Tephrosia purpurea seed is a valuable medicinal shrubby and woody plant which has been valued for centuries in ayurvedic medicine. Phyto-chemical analysis of aqueous, ethyl acetate and hexane T. purpurea seed extracts revealed the presence of various bioactive phytochemical compounds in all three extracts. The study was aimed to evaluate the anti inflammatory activity of different extracts of T. purpurea by HRBC membrane stabilization and protein denaturation method. The result showed aqueous extract of T. purpurea highest membrane stabilizing activity (85.6± 9.48) and protein inhibition activity (73.1± 8.78) at the concentration of 500 μg, when compared to diclofenac sodium. The result obtained from this study suggests that plant is may be a good natural source for anti-inflammatory therapy.

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Keywords

Tephrosia purpurea, phytochemical analysis, Anti-inflammatory, HRBC, Protein denaturation.

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