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Asian Journal of Pharmaceutical Research
Year : 2020, Volume : 10, Issue : 3
First page : ( 217) Last page : ( 220)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.5958/2231-5691.2020.00037.4

Comparative study of conventional and microwave assisted synthesis of some organic reactions

Yadav Akshay R.*, Mohite Shrinivas K., Magdum Chandrakant S.

Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Maharashtra, India-415404

*Corresponding Author E-mail: akshayyadav24197@gmail.com

Online published on 16 September, 2020.

Abstract

Microwave assisted organic synthesis has as a new “lead” in the organic synthesis. The technique offers clean, simple, efficient, fast and economic for the synthesis of a number of organic molecules such reaction has new tool in the organic synthesis. Conventional method of organic synthesis usually requires longer heating time, tedious apparatus setup which result in higher cost of process and the excessive use of solvents or reagents lead to environmental pollution. This technique is considered as important approach toward green chemistry because this technique is more environments friendly and this technology is used in the laboratory and has the potential to have a large impact on the fields of combinatorial chemistry. The microwave reactions were performed using microwave assisted synthesis on microwave, the reactions were worked up extensively to obtain a pure form of product which was isolated using literature work-up procedures. The products were further recrystallized with suitable solvents. The reactions were monitored with TLC intermittently for microwave assisted synthesis and hourly for conventional method of synthesis.

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Keywords

Conventional method, Green chemistry, Combinatorial chemistry, Microwave reactions.

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