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Asian Journal of Pharmaceutical Research
Year : 2020, Volume : 10, Issue : 2
First page : ( 105) Last page : ( 109)
Print ISSN : 2231-5683. Online ISSN : 2231-5691.
Article DOI : 10.5958/2231-5691.2020.00020.9

Formulation and Evaluation of Bioadhesive Buccal Drug Delivery of Sumatriptan Succinate Tablets

Dr. Reddy Y. Krishna*, Tasleem Juveria

Department of Pharmaceutics, Nalanda College of Pharmacy, Jawaharlal Nehru Technological University, Hyderabad, Telangana

*Corresponding Author E-mail: rajinisuralabs1@gmail.com

Online published on 3 June, 2020.

Abstract

The objective of this study was to develop effective buccal tablets of Sumatriptan Succinate. Tablets of Sumatriptan Succinate were prepared by direct compression method using bioadhesive polymers like Poloxamer188, β-CD, HPMC K4M. Buccal tablets were prepared by taking polymers in different ratios. The formulation F9 showed maximum drug release (98.92%) in 8 hrs. It was considered as optimized formulation.

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Keywords

Sumatriptan Succinate, Buccal tablets, Poloxamer188, β-CD, HPMC K4M, in-vitro drug release.

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