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Asian Journal of Pharmaceutical Analysis
Year : 2019, Volume : 9, Issue : 3
First page : ( 177) Last page : ( 190)
Print ISSN : 2231-5667. Online ISSN : 2231-5675.
Article DOI : 10.5958/2231-5675.2019.00031.0

Inclusive Review on Analytical and Bioanalytical Profile of Nifedipine

Tayade Ankita B.*, Patil Amod S., Jain Priti, Surana Sanjay J., Shirkhedkar Atul A.

R. C. Patel Institute of Pharmaceutical Education and Research, Karwand Naka, Shirpur, Dist. Dhule (MS) India, 425405

*Corresponding Author E-mail: taydeankita28@gmail.com

Online published on 31 December, 2019.

Abstract

Nifedipine (NIF) is calcium channel antagonist broadly used for management of numerous cardiovascular diseases. It is a photolabile drug that gets easily degraded when exhibit to sunlight and is lipophilic in nature. The review presented here systematizes various analytical and bio-analytical methods developed for Nifedipine alone and in combination with other drugs. It represents a comprehensive data of UV-Visible spectroscopy, HPTLC, HPLC, GC, Voltametric method and LC-MS methods reported by various scientists on Nifedipine for last 38 years (1980–2018).

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Keywords

Chromatography, Nifedipine, Analytical and Bioanalytical method, Development, Validation, Review article.

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