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Asian Journal of Pharmaceutical Analysis
Year : 2019, Volume : 9, Issue : 3
First page : ( 123) Last page : ( 127)
Print ISSN : 2231-5667. Online ISSN : 2231-5675.
Article DOI : 10.5958/2231-5675.2019.00023.1

Punica granatum root (s): Phytocompounds analysis, Anti-oxidant and Anti-microbial activity

Balaji E. Vignesh*, Selvan A Tamil, Srinivasan A, Nandhini S

PSG College of Pharmacy, Department of Pharmacology, Coimbatore-641004

*Corresponding Author E-mail: vigneshra96@gmail.com

Online published on 31 December, 2019.

Abstract

Punica granatum (PG) root (s) commonly known as pomegranate is a member of the monogeneric family, Punicaceae and is found throughout the world. Its phytocompounds possess numerous biological and toxicological properties including anti-oxidant, anti-inflammatory, anticancer and anti-angiogenesis activities. The present study was aimed to investigate anti-oxidant activity. Antioxidant potential was evaluated by the percentage inhibition of free radicals production by hydrogen peroxide method, which showed concentration dependent percentage inhibition of free radicals in both the methods. Also, the extract was analysed using HPTLC and GC-MS for the confirmation of active phyto compounds responsible for the desired biological activity. Furthermore, anti-microbial activity was done by disc diffusion and cup plate method. The zone of inhibition was evaluated by the test and standard sample.

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Keywords

Punica granatum (L) root(s), HPTLC, GC-MS, Hydrogen peroxide, Cup plate and Disc diffusion.

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