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Asian Journal of Pharmaceutical Analysis
Year : 2019, Volume : 9, Issue : 3
First page : ( 113) Last page : ( 117)
Print ISSN : 2231-5667. Online ISSN : 2231-5675.
Article DOI : 10.5958/2231-5675.2019.00021.8

Determination and Development of UV-Spectrophotometric method for the Amodiquine Hydrochloride by using quality by design (QBD) approach

Ashok Patil Karishma1, Dinkar Firke Sandip2,*

1Research Scholar, R. C. Patel Institute of Pharmaceutical Education and Research, Shipur, Dhule (425405)

2Professor, Pharmaceutical Chemistry Department, R. C. Patel Institute of Pharmaceutical Education and Research, Shipur, Dhule (425405)

*Corresponding Author E-mail: sandipfirke@rediffmail.com

Online published on 31 December, 2019.

Abstract

To develop a simple, accurate, and inexpensive UV sepectrometric method for the determination of the Amodiquine hydrochloride by using quality by design (QbD) approach. The double beam spectrophotometer of Shimadzu UV-1800 by using a determination of UV spectrophotometer method. The amodiquine Hydrochloride is soluble with Distilled Water & methanol (9: 1) as solvent and wavelength of 341 nm was selected as of 0.998. The (LOD) and (LOQ) were amodiquine Hydrochloride recovery was found to be 99.6%.

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Keywords

Quality by design, Amodiquine hydrochloride estimation, Spectrophotometric estimation.

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