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Asian Journal of Pharmaceutical Analysis
Year : 2019, Volume : 9, Issue : 2
First page : ( 62) Last page : ( 66)
Print ISSN : 2231-5667. Online ISSN : 2231-5675.
Article DOI : 10.5958/2231-5675.2019.00013.9

Chromatographic Estimation of Niacinamide in Anti aging Dermatological product

Banik Kabita*, Dr. Rath Simhachalam, Dr. Gupta B K

BCDA College of Pharmacy and Technology, Pharmaceutics Department, Kolkata, West Bengal

*Corresponding Author E-mail: Banikkabita64@gmail.com

Online published on 3 July, 2019.

Abstract

In this study Niacinamide based skin creams were formulated and evaluated. Niacinamide (also known as nicotinamide, 3-pyridinecarboxamide) is the physiologically active form of niacin or vitamin B3. Niacinamide, a derivative of niacin, has the ability to treat some skin conditions including aging skin. Quality evaluation of the product was assessed by using determination of Niacinamide content by HPTLC method and different evaluation methods. No change of the physical properties was observed; the pH was in a proper range. The formulations showed good spreadability, no evidence of phase separation and good consistency during this study period. From the present study it can be concluded that it is possible to develop creams containing Niacinamide having antiaging property and can be used as the provision of a barrier to protect skin.

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Keywords

Niacinamide, HPTLC, NADH and NADPH, Antiaging.

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