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Asian Journal of Pharmaceutical Analysis
Year : 2017, Volume : 7, Issue : 4
First page : ( 239) Last page : ( 242)
Print ISSN : 2231-5667. Online ISSN : 2231-5675.
Article DOI : 10.5958/2231-5675.2017.00039.4

A Review on Analytical Techniques for Estimation of Anti Cholinergic Drug: Glycopyrronium Bromide

Patel Khushboo*, Patel Dhara, Dwivedi Jaya, Newal Priyanka, Meshram Dhananjay

Department of Quality Assurance, Pioneer Pharmacy Degree College, Vadadara, Gujarat, India

*Corresponding Author E-mail: khushboopatel122@gmail.com

Online published on 2 June, 2018.

Abstract

Glycopyrronium bromide is a Anticholinergic class of drug indicated for the treatment of chronic obstructive pulmonary drug. Various analytical methods used for the estimation of Glycopyrronium bromide has been reviewed in this paper. These include Ultraviolet spectrometry, High performance thin layer chromatography, High performance liquid chromatography, Ion pair, to determine the amount of Glycopyrronium bromide in bulk drugs and pharmaceutical formulations and Biological Fluids. Stability indicating and impurity profiling methods for Glycopyrronium bromide are also described. These analytical methods can be used for qualitative and quantitative estimation of Glycopyrronium bromide and/or its related impurities or degradants in bulk and formulation.

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Keywords

Glycopyrronium bromide, analytical methods, estimation, formulation and Biological Fluids.

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