(54.237.183.249)
Users online: 2425    [ij] [ij] [ij] 
Email id
 

Asian Journal of Pharmaceutical Analysis
Year : 2020, Volume : 10, Issue : 3
First page : ( 158) Last page : ( 164)
Print ISSN : 2231-5667. Online ISSN : 2231-5675.
Article DOI : 10.5958/2231-5675.2020.00029.0

Development and validation of stability indicating uplc method for the simultaneous estimation of drugs in combined dosage forms using quality by design approach

Bhavani P. Geetha1,*, Devi D. Akila2

1Research Scholar, Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Pallavaram, Chennai-600117

2Associate Professor, Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Pallavaram, Chennai-600117

*Corresponding Author E-mail: akilaajcp@gmail.com

Online published on 16 September, 2020.

Abstract

UPLC is a modern technique which gives a new direction for liquid chromatography. UPLC refers to ultra performance liquid chromatography, which enhance mainly in three areas: speed, resolution and sensitivity. Ultra performance liquid chromatography (UPLC) applicable for particle less than 2μm in diameter to acquire better resolution, speed, and sensitivity compared with high-performance liquid chromatography (HPLC). The concept of “Quality by Design” (QbD) is an approach which covers a better scientific understanding of critical process and product qualities, designing controls and tests based on the scientific limits of understanding during the development phase and using the knowledge obtained during the life-cycle of the product to work on a constant improvement environment.

Top

Keywords

Ultra performance liquid chromatography, Resolution.

Top

  
║ Site map ║ Privacy Policy ║ Copyright ║ Terms & Conditions ║ Page Rank Tool
446,709,606 visitor(s) since 30th May, 2005.
All rights reserved. Site designed and maintained by DIVA ENTERPRISES PVT. LTD..
Note: Please use Internet Explorer (6.0 or above). Some functionalities may not work in other browsers.