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Asian Journal of Pharmaceutical Analysis
Year : 2020, Volume : 10, Issue : 1
First page : ( 27) Last page : ( 31)
Print ISSN : 2231-5667. Online ISSN : 2231-5675.
Article DOI : 10.5958/2231-5675.2020.00006.X

Effect of Poorna Chandrodayam Chendooram (PCM-Metallic Drug) on Lipid Profile, Liver Function and Kidney Function Parameters of Rats

Dr. Muthukumaran P.1,*, Dr. Begum V. Hazeena2

1Senior Lecturer, Faculty of Science, DMI St. Eugene University, P. O. Box: 330081, Plot No. B2029/M, 9 Miles, Great North Road, Chibombo, Zambia

2Former Dean and Head, Department of Siddha Medicine, Faculty of Science, Tamil University, Thanjavur, Tamil Nadu, India

*Corresponding Author E-mail: kumaran.bio14@gmail.com

Online published on 3 June, 2020.

Abstract

Poorna Chandrodayam Chendooram (PCM), a Siddha Herbal preparation which is used for its effect on liver function, kidney function and lipid profile after administrations into the biological system. The existing study was intended at evaluating the Liver, kidney and Lipid profile of Normal and PCM treated in investigational animal model. The experimental animal model was of Male rats. Male rats were divided into Two groups: control rats and Poornachandrodaya chenduram treated Rats. Triglycerides (TG) Total cholesterol (TC), and low density lipoprotein (LDL) were decreased in experimental groups whereas high density lipoprotein (HDL) were a little increased in male rats. The Total protein and albumin Level of plasma were enhanced very high significantly. In case of bilirubin, the decline was negligible for rats. The serum glutamic pyruvic transaminase (sGPT), serum glutamic oxaloacetic transaminase (sGOT) and alkaline phosphatase (ALP) content in the plasma were diminished very high significantly in the experimental groups. Creatinine, and urea were diminished in male where only change of uric acid level was significant increased. It is confirmed that Metal base drug PCM is a safe and effective drug. It is evident that the trial drug eliminate the toxic substances from the body and enhances the longevity of life.

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Keywords

PCM, TG, TC, LDL, HDL, SGPT, SGPT and ALP.

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