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Year : 2021, Volume : 11, Issue : 2
First page : ( 647) Last page : ( 660)
Online ISSN : 2249-7137.
Article DOI : 10.5958/2249-7137.2021.00409.2

Endoscopic picture of the gastroduodenal zone of patients with rheumatoid arthritis who received nonsteroidal anti-inflammatory drugs

Tukhtaeva N. Kh.1, Karimov M. Sh.1, Abzalova D.A.1, Khasanova G.Kh.1

1Tashkent Medical Academy, Uzbekistan

Online published on 3 April, 2021.


In this article, based on a retrospective analysis of case histories of patients with RA, presented data research pathology GDD to the extent of disease activity, duration of history and the failure of the joints, as well as the characteristics of ongoing pharmacotherapy. The results show that the pathology GDD in RA patients are often, in every fifth patient is a concomitant disease, and every tenth - is manifested in the form of clinical symptoms, the main causes of gastro duodenal lesions are viscera's, long-term course of the disease and the frequent use of NSAIDs and corticosteroids. Objective: To study the frequency of occurrence of lesions of the gastro duodenal zone and the frequency of drug use in patients with rheumatoid arthritis based on the materials of a retrospective analysis. Material and methods: a retrospective analysis of220 case histories of patients with rheumatoid arthritis (RA) treated in the rheumatology department of the III clinic of TMA was carried out. The selection condition was the endoscopic established diagnosis, that is, the presence of endoscopic examination. The state of the gastro duodenal zone (GDZ) and the pharmacotherapy of the underlying disease were evaluated. The results of the study show that GDZ pathology in RA patients is quite common, every third patient has symptoms of GDZ lesion and this is due not only to the intake of NSAIDs, but also due to the primary involvement of the GDZ mucosa in the pathological process.



Rheumatoid Arthritis, Gastric Ulcer, Gastritis, Nsaids, Corticosteroid.


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