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ACADEMICIA: An International Multidisciplinary Research Journal
Year : 2020, Volume : 10, Issue : 11
First page : ( 2273) Last page : ( 2280)
Online ISSN : 2249-7137.
Article DOI : 10.5958/2249-7137.2020.01609.2

Efficacy of rosuvastatin and ezetimib combination for diabetic dyslipidemia in patients with type 2 diabetes

Urunbaeva D.A., Akramkhuzhaeva A.B.

Tashkent Medical Academy, Uzbekistan

Abstract

One of the necessary drugs for the treatment of diabetic dyslipidemia affecting lipid metabolism is hydroxycis-methylglutaryl-coenzyme A-reductase inhibitors (statins) [2] and ezetimibe, which blocks the absorption of cholesterol in the epithelium of the small intestine, thereby preventing erythematic enterohepatic circulation of cholesterol [2,4]. Their effectiveness in correcting atherogenic dyslipidemia (DLP) and preventing macroangiopathieshas been studied in patients with diabetes mellitus (DM). The aim of this study was to study the lipid-lowering efficacy of the combination therapy of rosuvastatin with ezithymibe in patients with type 2 diabetes mellitus

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Keywords

Diabetes Mellitus (DM), Lipid-Lowering Therapy, Rosuvastatin, Ezetimibe, Total Cholesterol (TC), Low Dencity Lipoproteins (LDL), High Dencity Lipoproteins (HDL).

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